This work aimed to characterize the physicochemical and physiological changes (respiration rate, ethylene production, weight loss, firmness, color, soluble solids, pH, and titratable acidity) of three soursop varieties (GUANAY-1, GUANAY-2, and GUANAY-3) stored at 28 °C ± 1 and 15 °C ± 1. Fruits stored at 28 °C ± 1 reached the highest respiration rate on day seven, while those at 15 °C ± 1 exhibited a delayed climacteric peak. GUANAY-3 showed the lowest weight loss and firmness at 28°C ± 1 (p<0.05), whereas GUANAY-1 demonstrated an extended postharvest life of 11 days at 15°C ± 1, maintaining minimal weight loss and firmness reduction. Across storage temperatures, fruit color progressively darkened as ripening advanced. Soluble solids, pH, and acidity peaked on day seven at 28°C ± 1, coinciding with the climacteric peak. At 15 °C ± 1, these parameters peaked on day nine for GUANAY-1, while GUANAY-2 and GUANAY-3 reached their highest values on day seven. Multivariate analysis revealed that GUANAY-2 and GUANAY-3 shared similar postharvest traits on day five at 28 °C ± 1, while all varieties presented comparable characteristics on days five and seven at 15 °C ± 1. Significant correlations were observed between pH and firmness, as well as weight loss and acidity at both temperatures. GUANAY-3 at 28 °C ± 1 and GUANAY-1 at 15 °C ± 1 exhibit promising potential for national and international markets, improving postharvest management strategies or enhancing marketability.