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Mini Reviews

Vol. 1 No. 3 (2014)

Electrospun plant-derived natural biomaterials for Tissue engineering

DOI
https://doi.org/10.14719/pst.2014.1.3.65
Submitted
26 May 2014
Published
15-08-2014

Abstract

Plant-derived natural products are being used in medicine, and they are easily available for the production and use in tissue engineering based biological applications. Utilization of plant materials to treat human diseases is a common practice followed over many decades. In fact plant and its derivatives have been actively included in health management over thousands of years. The advent of phytochemical and phytopharmacological sciences has opened an arena to elucidate the structural and biological composition of several medicinal plant products. Their pharmacological effects depend on the supply of highly active water soluble compounds; however, due to their large molecular size most compounds are unable to cross the lipid membranes of the cells and therefore result in poor absorption resulting in loss of bioavailability and efficacy. Electrospinning makes it possible to combine the advantages of utilizing these plant materials in the form of nanofibrous scaffolds for delivering the active constituent at a sufficient concentration during the entire treatment period to the host site. The aim of this review is to highlight the potential applications of electrospun nanofibrous scaffolds based systems and herbal medicines in tissue engineering.

References

  1. Kimberley, T., Suganya, C., Venugopal, J., Biswas, A., Mahesh, C., Ramakrishna, S., ... & Fong, C. A. (2014). Nanoscaffold Impregnated With Human Wharton's Jelly Stem Cells or Its Secretions Improves Healing of Wounds. Journal of Cellular Biochemistry, 115(4), 794-803. PMid:24265214 http://dx.doi.org/10.1002/jcb.24723
  2. Krishnan, R., Rajeswari, R., Venugopal, J., Sridhar, R., Shayanti, M., & Ramakrishna, S. (2012). Polysaccharide nanofibrous scaffolds as a model for in vitro skin tissue regeneration. Journal of Materials Science: Materials in Medicine, 23, 1511–1519. PMid:22491895 http://dx.doi.org/10.1007/s10856-012-4630-6
  3. Morris, V. J. (2011). Emerging roles of engineered nanomaterials in the food industry. Trends in Biotechnology, 29, 509-516. http://dx.doi.org/10.1016/j.tibtech.2011.04.010 PMid:21664709
  4. Suganya, S., Venugopal, J., Ramakrishna, S., Lakshmi, B., & Giri Dev, V. R. (2014)a. Aloe vera incorporated biomimetic nanofibrous scaffold: a regenerative approach for skin tissue engineering. Iran Polymer Journal, 23(3), 237-248. http://dx.doi.org/10.1007/s13726-013-0219-2
  5. Suganya, S., Venugopal, J., Ramakrishna, S., Lakshmi, B., & Giri Dev, V. R. (2014)b. Herbally Derived Polymeric Nanofibrous Scaffolds for Bone Tissue Regeneration. Journal of Applied Polymer Science, 131, 9835 (1-11). http://dx.doi.org/10.1002/app.39835
  6. Suganya, S., Venugopal, J., Ramakrishna, S., Lakshmi, B., & Giri Dev, V. R. (2014)c. Aloe vera/Silk Fibroin/Hydroxyapatite Incorporated Electrospun Nanofibrous Scaffold for Enhanced Osteogenesis. Journal of Biomaterials Applications, 4(1), 9-19. http://dx.doi.org/10.1177/0885328213513934
  7. Venugopal, J., Molamma, P., Shayanti, M., Rajeswari, R., & Ramakrishna, S. (2012). Biomaterial strategies for alleviation of Myocardial Infarction. Journal of Royal Society Interface, 9, 1-19. http://dx.doi.org/10.1098/rsif.2011.0301 PMid: 21900319
  8. Venugopal, J., Shayanti, M., Rajeswari, R., Sridhar, R., & Ramakrishna, S. (2013)a. Xylan polysaccharides fabricated into nanofibrous substrate for Myocardial Infarction. Materials Science and Engineering C, 33, 1325–1331. PMid:23827578 http://dx.doi.org/10.1016/j.msec.2012.12.032
  9. Venugopal, J., Sridhar, R., Rajeswari, R., Shayanti, M., Balamurugan, R., & Ramakrishna S. (2013)b. Nanofibrous structured Biomimetic Strategies for Skin Tissue Regeneration. Wound Repair and Regeneration, 21, 1–16. PMid:23126632. http://dx.doi.org/10.1111/j.1524-475X.2012.00861.x

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